STACHYBOTRIN-C AND PARVISPORIN, NOVEL NEURITOGENIC COMPOUNDS .1. TAXONOMY, ISOLATION, PHYSICOCHEMICAL AND BIOLOGICAL PROPERTIES

Authors
NOZAWA Y YAMAMOTO K ITO M SAKAI N MIZOUE K MIZOBE F HANADA K
Citation
Y. Nozawa et al., STACHYBOTRIN-C AND PARVISPORIN, NOVEL NEURITOGENIC COMPOUNDS .1. TAXONOMY, ISOLATION, PHYSICOCHEMICAL AND BIOLOGICAL PROPERTIES, Journal of antibiotics, 50(8), 1997, pp. 635-640
Citations number
18
Categorie Soggetti
Pharmacology & Pharmacy",Immunology,"Biothechnology & Applied Migrobiology
Journal title
Journal of antibiotics → ACNP
ISSN journal
00218820
Volume
50
Issue
8
Year of publication
1997
Pages
635 - 640
Database
ISI
SICI code
0021-8820(1997)50:8<635:SAPNNC>2.0.ZU;2-6
Abstract
Stachybotrin C and parvisporin, novel neuritogenic compounds, were iso lated from the culture broth of Stachybotrys parvispora F4708. Stachyb otrin C induced significant neurite outgrowth in PC12 cells and showed cell survival activity in the primary culture of cerebral cortical ne urons. Parvisporin demonstrated only weak neuritogenic activity.