ISOLATION AND STRUCTURE ELUCIDATION OF 7,8-DIDEOXY-6-OXO-GRISEORHODIN-C PRODUCED BY ACTINOPLANES IANTHINOGENES

Authors
PANZONE G TRANI A FERRARI P GASTALDO L COLOMBO L
Citation
G. Panzone et al., ISOLATION AND STRUCTURE ELUCIDATION OF 7,8-DIDEOXY-6-OXO-GRISEORHODIN-C PRODUCED BY ACTINOPLANES IANTHINOGENES, Journal of antibiotics, 50(8), 1997, pp. 665-670
Citations number
11
Categorie Soggetti
Pharmacology & Pharmacy",Immunology,"Biothechnology & Applied Migrobiology
Journal title
Journal of antibiotics → ACNP
ISSN journal
00218820
Volume
50
Issue
8
Year of publication
1997
Pages
665 - 670
Database
ISI
SICI code
0021-8820(1997)50:8<665:IASEO7>2.0.ZU;2-8
Abstract
A novel product, isolated from a culture broth of Actinoplanes ianthin ogenes fermented for producing purpuromycin, was purified and its stru cture established on the basis of physico-chemical data and chemical r eactions. The new product resulted to be structurally related to grise orhodins, a group of hydroquinonic antibiotics obtained from Streptomy ces californicus. This compound showed a weak activity against Gram-po sitive and resulted inactive against Gram-negative bacteria and Candid a albicans.