BIOCONVERSION OF SUBSTITUTED NAPHTHALENES TO THE CORRESPONDING 1,2-DIHYDROXY DERIVATIVES BY ESCHERICHIA-COLI RECOMBINANT STRAINS

Authors
DIGENNARO P BESTETTI G GALLI E ORSINI F PELIZZONI F SELLO G
Citation
P. Digennaro et al., BIOCONVERSION OF SUBSTITUTED NAPHTHALENES TO THE CORRESPONDING 1,2-DIHYDROXY DERIVATIVES BY ESCHERICHIA-COLI RECOMBINANT STRAINS, Tetrahedron letters, 38(35), 1997, pp. 6267-6270
Citations number
14
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
38
Issue
35
Year of publication
1997
Pages
6267 - 6270
Database
ISI
SICI code
0040-4039(1997)38:35<6267:BOSNTT>2.0.ZU;2-2
Abstract
1,2-dihydroxynaphthalenes are produced by bioconversion of the corresp onding hydrocarbons using Escherichia coli recombinant strains contain ing the naphthalene dioxygenase and dehydrogenase genes cloned from Ps eudomonas fluorescens N3. Conversions are lead by a two step procedure without isolation of the dihydrodiol intermediate. Conversion rates d epend on the position and nature of the naphthalene substituent (C) 19 97 Elsevier Science Ltd.