DETECTION OF MORPHINE IN PPB RANGE BY USING SPR (SURFACE-PLASMON-RESONANCE) IMMUNOSENSOR

Authors
MIURA N OGATA K SAKAI G UDA T YAMAZOE N
Citation
N. Miura et al., DETECTION OF MORPHINE IN PPB RANGE BY USING SPR (SURFACE-PLASMON-RESONANCE) IMMUNOSENSOR, Chemistry Letters, (8), 1997, pp. 713-714
Citations number
5
Categorie Soggetti
Chemistry
Journal title
Chemistry Letters → ACNP
ISSN journal
03667022
Issue
8
Year of publication
1997
Pages
713 - 714
Database
ISI
SICI code
0366-7022(1997):8<713:DOMIPR>2.0.ZU;2-R
Abstract
Highly sensitive detection of morphine (MO) in ppb range was realized by using an immunosensor based on surfaceplasmon-resonance (SPR) pheno mena. The addition of MO into the antibody solution was found to reduc e the incident angle shift of the SPR sensor system sharply because of the inhibition effect of MO. Based on this inhibiting principle, the present sensor could detect MO very sensitively in the concentration r ange of 0.1 - 10 ng/cm(3) (ppb).