GENETIC INTERACTIONS OF HOX GENES IN LIMB DEVELOPMENT - LEARNING FROMCOMPOUND MUTANTS

Authors
RIJLI FM CHAMBON P
Citation
Fm. Rijli et P. Chambon, GENETIC INTERACTIONS OF HOX GENES IN LIMB DEVELOPMENT - LEARNING FROMCOMPOUND MUTANTS, Current opinion in genetics & development, 7(4), 1997, pp. 481-487
Citations number
35
Categorie Soggetti
Biology,"Cell Biology","Biothechnology & Applied Migrobiology","Genetics & Heredity
Journal title
Current opinion in genetics & development → ACNP
ISSN journal
0959437X
Volume
7
Issue
4
Year of publication
1997
Pages
481 - 487
Database
ISI
SICI code
0959-437X(1997)7:4<481:GIOHGI>2.0.ZU;2-L
Abstract
The recent generation of mice harboring multiple mutations in Hox gene s has highlighted the role of these genes in controlling growth and pa tterning of the limb bud. Tt le study of the phenotypes has not only r evealed a complex network of genetic interactions among paralogous and non-paralogous Abdominal-B-related Hox genes but has also refined our understanding of their function.