EXCITATORY AMINO-ACID RECEPTORS IN THE BASOLATERAL AMYGDALA REGULATE ANXIETY RESPONSES IN THE SOCIAL-INTERACTION TEST

Authors
SAJDYK TJ SHEKHAR A
Citation
Tj. Sajdyk et A. Shekhar, EXCITATORY AMINO-ACID RECEPTORS IN THE BASOLATERAL AMYGDALA REGULATE ANXIETY RESPONSES IN THE SOCIAL-INTERACTION TEST, Brain research, 764(1-2), 1997, pp. 262-264
Citations number
18
Categorie Soggetti
Neurosciences
Journal title
Brain research → ACNP
ISSN journal
00068993
Volume
764
Issue
1-2
Year of publication
1997
Pages
262 - 264
Database
ISI
SICI code
0006-8993(1997)764:1-2<262:EARITB>2.0.ZU;2-K
Abstract
Blocking GABA(A) receptors in the basolateral amygdala (BLA) elicits i ncreases in heart rate (HR), blood pressure (BP) and anxiety responses by enhancing a glutamate mediated excitation. The present study was c onducted to determine the role of the ionotropic glutamate receptors w ithin the BLA in regulating HR, BP and experimental anxiety. Blocking basal glutamate excitation had no significant effect on HR or BP, but did elicit a significant anxiolytic-like effect. (C) 1997 Elsevier Sci ence B.V.