The relationship between aspirin use and colorectal cancer risk was ex
amined by a case-control study in Italy. Regular aspirin use was repor
ted by only 47 (3.5%) cases and 77 (4.1%) control subjects, giving a m
ultivariate odds ratio (OR) of 0.7 (95% CI 0.5-1.0) after allowance fo
r education, physical exercise and selected dietary factors.