BACKGROUND: The optimal material for carotid patch angioplasty after e
ndarterectomy remains uncertain, This study compares the early outcome
and recurrent stenosis rates between saphenous vein (SV) and expanded
polytetrafluoroethylene (ePTFE) carotid patch angioplasty, METHODS: T
he results of 421 consecutive carotid endarterectomies performed over
a 72-month period were reviewed. Postoperative complications and reste
nosis rates, defined as greater than or equal to 60% narrowing measure
d by color flow duplex, were compared. RESULTS: Patch angioplasty was
performed with SV in 287 and with ePTFE in 110 cases. Patients who had
undergone primary closure (n = 20) or whose form of closure was unkno
wn (n = 4) were excluded. The mean age of patients and length of follo
w-up was similar between groups. Women were more likely to be patched
with ePTFE than were men (36% versus 23%, P = 0.02). One death occurre
d in each group (0.3% SV, 0.9% ePTFE, P = 0.47), and four strokes occu
rred in each group (1.4% SV, 3.6% ePTFE, P = 0.22), Cervical hematomas
requiring operative evacuation occurred in five SV closures and in th
ree ePTFE closures (1.7% versus 2.1%, P = 0.69). Vein harvest site com
plications occurred in 6 patients (2%) who had undergone SV patch angi
oplasty. Recurrent stenosis occurred in 3 patients with SV closure and
in 3 patients with ePTFE closure (1.0% versus 2.7%, P = 0.35). The 60
-month restenosis rates by life table analysis were 2.6% +/- 2.1% for
SV and 10.7% +/- 7.9% for ePTFE (P = 0.17). CONCLUSIONS: The incidence
of postoperative complications is similar with SV or ePTFE patch angi
oplasty; however, Vein harvest site complications are avoided with the
use of ePTFE. Recurrent stenosis at 5 years occurs infrequently with
either SV or ePTFE. (C) 1997 by Excerpta Medica Inc.