SYNTHESIS OF PYRIMIDOPYRAZOLOQUINOLINE AND QUINONOPYRAZOLOQUINAZOLINETRIONE DERIVATIVES

Authors
HASSAN AA MEKHEIMER R MOHAMED NK
Citation
Aa. Hassan et al., SYNTHESIS OF PYRIMIDOPYRAZOLOQUINOLINE AND QUINONOPYRAZOLOQUINAZOLINETRIONE DERIVATIVES, Die Pharmazie, 52(8), 1997, pp. 589-593
Citations number
21
Categorie Soggetti
Pharmacology & Pharmacy",Chemistry
Journal title
Die Pharmazie → ACNP
ISSN journal
00317144
Volume
52
Issue
8
Year of publication
1997
Pages
589 - 593
Database
ISI
SICI code
0031-7144(1997)52:8<589:SOPAQ>2.0.ZU;2-U
Abstract
Pyrazolo[4,3-c]quinolines 1 interact with tetracyanoethylene (TCNE) an d 2-(dicyanomethylene)-1,3-indanedione (CNIND) to form the pyrimidopyr azoloquinolines 2a-g indenopyrimidopyrazoloquinolines 3a-g whereas on reaction with 2,3-dicyano-5,6-dichloro-1,4-benzoquinon (DDQ), 2,3,5,6- Tetrachloro-1,4-benzochinon (CHL) and 2,3,5,6-tetrabromo-1P-benzoquino ne (BRL) as well as 2,3-dichloro-1,4-naphthoquinone (DCHNQ) afforded t he quinonopyrazoloquinazolintrione derivatives 5 and 7.