BONE HISTOMORPHOMETRY IN EARLY DIAGNOSIS OF A MONOCLONAL GAMMOPATHY OF UNDETERMINED SIGNIFICANCE 10 YEARS BEFORE CLINICAL-EVIDENCE

Authors
PASCARETTI C CHAPPARD D LEGRAND E AUDRAN M BASLE MF
Citation
C. Pascaretti et al., BONE HISTOMORPHOMETRY IN EARLY DIAGNOSIS OF A MONOCLONAL GAMMOPATHY OF UNDETERMINED SIGNIFICANCE 10 YEARS BEFORE CLINICAL-EVIDENCE, Journal of histotechnology, 20(3), 1997, pp. 279-281
Citations number
9
Categorie Soggetti
Cell Biology
Journal title
Journal of histotechnology → ACNP
ISSN journal
01478885
Volume
20
Issue
3
Year of publication
1997
Pages
279 - 281
Database
ISI
SICI code
0147-8885(1997)20:3<279:BHIEDO>2.0.ZU;2-3
Abstract
Bone histomorphometry is a valuable method to detect early histologica l characteristic modifications in monoclonal gammopathies of undetermi ned significance (MGUS). We report a case in which a malignant gammopa thy had induced bone changes noticeable on the biopsy 12 years before clinical evidence of the disease. This case emphasize the importance o f bone histomorphometry as a predictive tool for MGUS.