H. Stankovicova et al., REACTION OF 4-OXOCHROMENE-3-CARBOXALDEHYDES WITH PRIMARY AMIDES AND BENZOTRIAZOLE OR 1H-1,2,4-TRIAZOLE, Collection of Czechoslovak Chemical Communications, 62(5), 1997, pp. 781-790
-oxochromen-3-yl)(1,2,4-triazol-3-yl)methyl]amides 5 and uted-4-oxochr
omen-3-yl)(benzotriazol-1-yl)methyl]a 6 were prepared by the reaction
of 6-substituted 4-oxochromene-3-carboxaldehydes 1 with primary amides
and 1H-1,2,4-triazole or 1H-benzotriazole. 6-Substituted 3-[hydroxy(1
,2,4-triazol-1-yl)methyl]chromen-4-one 2 and 6-substituted 3-[hydroxy(
benzotriazol-1-yl)methyl]chromen-4-one 3 were isolated as stable inter
mediates of these reactions. Beneficial effect of microwave irradiatio
n on length of reaction time was observed. Some reactions of these der
ivatives with O, S, and N nucleophiles are described.