MRI OF HISTOLOGICALLY CONFIRMED MAMMARY-CARCINOMA - CLINICAL RELEVANCE OF DIAGNOSTIC PROCEDURES FOR DETECTION OF MULTIFOCAL OR CONTRALATERAL SECONDARY CARCINOMA
A. Rieber et al., MRI OF HISTOLOGICALLY CONFIRMED MAMMARY-CARCINOMA - CLINICAL RELEVANCE OF DIAGNOSTIC PROCEDURES FOR DETECTION OF MULTIFOCAL OR CONTRALATERAL SECONDARY CARCINOMA, Journal of computer assisted tomography, 21(5), 1997, pp. 773-779
Purpose: MR mammography (MRM) is a sensitive diagnostic method for the
detection of mammary carcinomas. The present study evaluates whether
MRM can yield additional relevant data in cases of histologically conf
irmed mammary carcinoma.Method: Thirty-four patients with histological
ly confirmed mammary carcinoma were examined at MRM using a T1-weighte
d GE sequence and a T2-weighted SE sequence. Morphologic criteria and
the dynamic contrast medium behavior of the tumors were evaluated. Res
ults: MRM showed a 100% sensitivity and diagnostic accuracy in the det
ection of mammary carcinomas. Additionally, three unexpected contralat
eral carcinomas were discovered. In 26 patients, there was a multifoca
l or multicentric tumor process. In 24 patients, peritumoral edema was
visualized, which corresponded histologically in 21 patients with lym
phangiosis and in 3 with an inflammatory peritumoral reaction. Conclus
ion: Because of its high sensitivity in the diagnosis of multifocal di
sease and of contralateral carcinomas, MRM would seem to represent a u
seful addition to preoperative diagnostic procedures. The potential be
nefit to the patient and its cost efficiency, however, remain to be cl
arified.