RHABDOMYOSARCOMA - BIOLOGY AND TREATMENT

Authors
PAPPO AS SHAPIRO DN CRIST WM
Citation
As. Pappo et al., RHABDOMYOSARCOMA - BIOLOGY AND TREATMENT, The Pediatric clinics of North America, 44(4), 1997, pp. 953
Citations number
59
Categorie Soggetti
Pediatrics
Journal title
The Pediatric clinics of North America → ACNP
ISSN journal
00313955
Volume
44
Issue
4
Year of publication
1997
Database
ISI
SICI code
0031-3955(1997)44:4<953:R-BAT>2.0.ZU;2-9
Abstract
Rhabdomyosarcoma is the most common soft-tissue sarcoma of childhood. Recognition of specific genetic changes in the two most common subtype s of rhabdomyosarcoma has allowed better understanding of the pathogen esis of this disease. In addition, identification of prognostic factor s and the use of risk-directed multimodal therapy have improved the ou tcome for these patients significantly, with cure rates approaching 70 %.