Background: Stereotactic core needle biopsy (SCNB) is increasing in po
pularity and is currently being performed by both radiologists and sur
geons. It has been shown to be accurate and cost effective, but the ap
propriate use of SCNB in the probably benign mammographic lesion has n
ot been determined, Nor has it been determined whether a learning curv
e affects performance of the procedure. Study Design: The records of a
ll patients undergoing SCNB by the author from August 1993 through May
1996 were reviewed, Two hundred forty-two patients underwent 244 proc
edures, Indications for biopsy, results, and complications were examin
ed. Results: Probably benign mass Tvas, the most common indication for
biopsy (45%), and microcalcifications were the indication for biopsy
in 24%, A diagnosis of cancer nas made in 11.1%. Patients with microca
lcifications and probably benign masses were diagnosed with cancer in
18.4 and 1.8%, respectively. Three of eight patients undergoing open b
iopsy for atypical hyperplasia were diagnosed with cancer, Accuracy ra
te for the entire series was 97.7%, The effect of operator experience
on the indication for SCNB was studied, As experience increased from t
he first to the last third of the study, microcalcifications as an ind
ication increased from 23.5-47.5%, During this same time period, ''pro
bably benign'' mass decreased from 53.1-32.5%. Conclusion: This study
demonstrates that accuracy of this surgical series is comparable to ot
her published series, Biopsies for more difficult lesions were noted t
o increase as operator experience increased, It was Likely that this '
'learning curve'' was owing to improvements in technique and an increa
sed confidence ire the accuracy of the procedure, With an incidence of
cancer of less than 2% in patients with a probably benign mass, inter
val mammography represents for many, a cost-effective alternative. (C)
1997 by the American College of Surgeons.