E. Esser et W. Wagner, DENTAL IMPLANTS FOLLOWING RADICAL ORAL-CANCER SURGERY AND ADJUVANT RADIOTHERAPY, The International journal of oral and maxillofacial implants, 12(4), 1997, pp. 552-557
Following radical oral cancer surgery and postoperative adjuvant radio
therapy with a total dose of GO Gy, 71 IMZ and 150 Branemark implants
were placed in the mandibles and 28 Branemark implants were placed in
the maxillas of 60 patients between 1985 and 1995. Adjunctive hyperbar
ic oxygen therapy was not used. Osteoradionecrosis of the mandible occ
urred in two patients (3.4%), and necrosis of soft tissue in the floor
of the mouth region occurred in three patients (5.2%). Twenty-one imp
lants (18 in the mandible and 2 in the maxilla) were not osseointegrat
ed when surgically exposed. In subsequent follow-up, 17 mandibular imp
lants and 5 maxillary implants lost their osseointegration. The life t
able method indicated that 5-year actuarial implant success rates in t
he irradiated mandible were 77.5% for the IMZ system and 83.6% for the
Branemark system. These differences were not statistically significan
t. Retrospective analysis indicated that the success of implants in th
e irradiated mandible is determined after an interval of 18 to 24 mont
hs. For a small number of Branemark implants in the irradiated maxilla
, an actuarial success rate of 85.5% was found.