Furcation perforations created in the pulpal floors of 30 extracted hu
man molars were repaired with either light-cured glass ionomer cement
(GI), calcium phosphate cement (CPC), or light-cured glass ionomer cem
ent placed over a CPC matrix (M). After the cement was set, the teeth
were immersed in India Ink for 48 h, dried, and sectioned longitudinal
ly. Dye penetration into the furcation repair was independently evalua
ted by three board-certified endodontists. There was no significant di
fference in the mean extent of dye leakage among the three experimenta
l groups. The use of CPC, with its enhanced biocompatibility, potentia
l for osteoconduction, and sealing ability, may improve the prognosis
of teeth with furcation perforations.