NEW BOTRYDIAL SESQUITERPENOIDS FROM HYMENOSCYPHUS-EPIPHYLLUS

Authors
THINES E ANKE H STEGLICH W STERNER O
Citation
E. Thines et al., NEW BOTRYDIAL SESQUITERPENOIDS FROM HYMENOSCYPHUS-EPIPHYLLUS, Zeitschrift fur Naturforschung. C, A journal of biosciences, 52(7-8), 1997, pp. 413-420
Citations number
29
Categorie Soggetti
Biology
Journal title
Zeitschrift fur Naturforschung. C, A journal of biosciences → ACNP
ISSN journal
09395075
Volume
52
Issue
7-8
Year of publication
1997
Pages
413 - 420
Database
ISI
SICI code
0939-5075(1997)52:7-8<413:NBSFH>2.0.ZU;2-O
Abstract
Four new botrydial derivatives, hymendial (1), 7 alpha-hydroxydihydrob otrydial (2), 7 alpha-hydroxy-10-O-methyldihydrobotrydial (4), and 7 a lpha-acetoxy-15 alpha-methoxy-10-O-methyl-dihbotrydial (5) were isolat ed together with dihydrobotrydial (3) from the culture fluid of the as comycete Hymenoscyphus epiphyllus. In addition, cytochalasin H (6a), 1 8-deoxycytochalasin H (6b) and (+)-mellein (7) were produced by this f ungus. Hymendial (1), possessing an alpha, beta-unsaturated dialdehyde functionality, exhibits antimicrobial and cytotoxic activities and is mutagenic in the Ames Salmonella assay.