LARYNGEAL NECROSIS AFTER COMBINED CHEMOTHERAPY AND RADIATION-THERAPY

Post-radiation necrosis of the larynx is a major complication after ir radiation and has become rare. Recently, combined chemotherapy and rad iation therapy has been introduced for head and neck tumours. The auth ors report a case of laryngeal necrosis after combination therapy for a patient with cervical lymph node metastases of nasopharyngeal carcin oma and review the literature on late laryngeal necrosis. Although rad iation-induced laryngeal necrosis has become a rare complication, the combination of chemotherapy and radiation therapy may increase its inc idence. We should always consider it as a possible late complication a nd treat it appropriately.