Ja. Cianciola et al., DURATION AND INTENSITY OF ANESTHETIC EFFECT PRODUCED BY CANKER SORE MEDICATIONS, The Journal of clinical dentistry, 8(4), 1997, pp. 100-102
Canker sore medications are often recommended to patients for relief o
f pain associated with aphthous ulcers or other minor irritations of t
he mouth. The anesthetic effect of these medications is achieved by in
corporation of local anesthetics, such as benzocaine, into the product
s' formulations. To determine the duration and intensity of the anesth
etic effect of benzocaine-containing products, three topical oral heal
th care medications, Red Cross Canker Sore Medication, Maximum Strengt
h Anbesol and Orajel Mouth Aid, were compared. In this double blind cr
oss-over study, each product was tested on 21 subjects with normal muc
osa and gingiva. All three products produced anesthetic effects. Red C
ross Canker Sore Medication was shown to have the longest duration and
greatest intensity.