U. Buoncristiani et al., OXIDATIVE DAMAGE DURING HEMODIALYSIS USING A VITAMIN-E-MODIFIED DIALYSIS MEMBRANE - A PRELIMINARY CHARACTERIZATION, Nephron, 77(1), 1997, pp. 57-61
A comparison of the oxyradical exposure during hemodialysis (HD) carri
ed out with vitamin-E-modified cellulose (CL-E) or conventional membra
nes, studying red blood cell (RBC) and plasma lipoperoxidation and RBC
glutathione metabolism, was done. In this preliminary characterizatio
n of a new and original approach to the prevention of free radical dam
age in HD, the results obtained indicate that lipoperoxidation in plas
ma and RBC is decreased and therefore oxidative damage can be signific
antly decreased using CLE dialysis membranes instead of conventional m
embranes.