A multicenter cohort study was designed to assess pregnancy outcome am
ong natural family planning (NFP) users, and provide the opportunity t
o address complications in NFP users by planning status and by timing
of conception with respect to day of ovulation. There were 877 singlet
on births in this sample. Complications evaluated were abnormal vagina
l bleeding, urinary tract infection, vaginal infection, hypertension o
f pregnancy, proteinuria, glycosuria, and anemia. There was no signifi
cant difference in the mean age, number of prenatal visits or birth we
ight among optimally and non-optimally timed pregnancies or for planne
d and unplanned pregnancies. There were higher incidences of ''parity
2 or more'' and current smokers in the non-optimally timed pregnancies
and lower incidences of prior pregnancy loss and ''currently employed
'' in the non-optimally timed pregnancies. There was little difference
in pregnancy complications with respect to pregnancy timing, with the
exception of a significant increased risk of vaginal bleeding late in
pregnancy among non-optimally timed conceptions (11.5%) compared to o
ptimally timed pregnancies (5.2%, RR = 2.2, 95% CI 1.3-3.7). More diff
erences were observed in pregnancy complication rates by planning stat
us. Unplanned pregnancies were associated with significantly more late
pregnancy bleeding, vaginal infections, proteinuria, glycosuria and m
edication use than planned pregnancies. Unplanned pregnancies had lowe
r incidences of maternal anemia. Complications of pregnancy were low i
n this NFP population, irrespective of planned versus unplanned status
. Women with planned pregnancies had even fewer complications during p
regnancy than women with unplanned conceptions, suggesting that women
using NFP to plan their reproduction may be at particularly low risk.