SEPARATION AND TECHNETIUM LABELING OF AUTOLOGOUS POLYCLONAL IMMUNOGLOBULIN-G

Authors
KLADNIK S BUDIHNA NV BATAGELJ I GUBINA M
Citation
S. Kladnik et al., SEPARATION AND TECHNETIUM LABELING OF AUTOLOGOUS POLYCLONAL IMMUNOGLOBULIN-G, Nuclear medicine and biology, 24(6), 1997, pp. 535-538
Citations number
13
Categorie Soggetti
Radiology,Nuclear Medicine & Medical Imaging
Journal title
Nuclear medicine and biology
ISSN journal
09698051 → ACNP
Volume
24
Issue
6
Year of publication
1997
Pages
535 - 538
Database
ISI
SICI code
0969-8051(1997)24:6<535:SATLOA>2.0.ZU;2-1
Abstract
Autologous IgG were separated from rabbit sera and radiolabeled to per form scintigraphy. The IgG separation was accomplished with fast prote in liquid chromatography. IgG were directly labeled with Tc-99m using stannous tartrate as reducing agent, sterilized with membrane filter a nd injected into rabbits, The method can be adopted for use in humans. It is suitable for repeated use as there is no danger of allergic rea ction in the recipient. (C) 1997 Elsevier Science Inc.