J. Hyer et T. Mikawa, RETROVIRAL TECHNIQUES FOR STUDYING ORGANOGENESIS WITH A FOCUS ON HEART DEVELOPMENT, Molecular and cellular biochemistry, 172(1-2), 1997, pp. 23-35
The study of development has been revolutionized by the application of
molecular techniques, which make it possible to identify factors invo
lved in the developmental process. However, in order to correctly asse
ss the contribution of these growth factors, transcription factors, re
ceptors or signaling molecules, it is necessary to study them in the a
nimal as a whole; it is not enough to conclude that they must be impor
tant based on their expression patterns.