L. Singleton et al., LONG-TERM HOSPITALIZATION FOR TUBERCULOSIS-CONTROL - EXPERIENCE WITH A MEDICAL-PSYCHOSOCIAL INPATIENT UNIT, JAMA, the journal of the American Medical Association, 278(10), 1997, pp. 838-842
Context.-Patients with tuberculosis (TB) who are nonadherent to therap
y or have complicated medical or social problems pose a threat to publ
ic health. In some cases, hospitalization may be a necessary component
of a comprehensive TB control program. Objective.-To describe experie
nce with a new inpatient program for TB control.Design.-Retrospective
review. Setting.-Eighteen-bed, secure, TB treatment unit in a state pu
blic health hospital providing a spectrum of acute and chronic care se
rvices. Patients.-Patients with known or suspected TB who were unable
to be treated as outpatients and were hospitalized from 1990 through 1
995. Interventions.-voluntary or involuntary hospitalization, with med
ical, psychosocial, and legal services. Main Outcome Measures.-Admissi
ons, treatment completion, and disposition. Results.-A total of 166 pa
tients with a confirmed diagnosis of TB accounted for 214 hospitalizat
ions for TB. The mean age was 42 years, 132 (79.5%) were men, 84 (50.6
%) were nonwhite, and 45 (27.1%) were foreign born. At the time of adm
ission, 58 patients (34.5%) were homeless, 116 (69.9%) had a history o
f abuse of alcohol or other drugs, and 46 (31.7%) were positive for hu
man immunodeficiency virus. The mean length of stay was 119.7 days (me
dian, 70 days; range, 7-656 days), and was higher among homeless patie
nts than nonhomeless patients (168.8 vs 93.4 days). Of 48 patients (28
.9%) who were admitted involuntarily, 21 required long-term confinemen
t under court order. Admission indications (not mutually exclusive) ch
anged over 5 years: nonadherence decreased (95% to 34%), medical compl
exity increased (14% to 77%), short-term isolation increased (19% to 3
9%), and involuntary admission decreased (54% to 13%). Of 157 patients
with positive cultures for Mycobacterium tuberculosis, 36 (23.1%) wer
e resistant to at least 1 drug, including 16 who were multidrug resist
ant. A total of 123 patients (74.7%) were discharged to an outpatient
setting to complete therapy, 40 (24.1%) required inpatient care to com
plete therapy, and 3 died (1 from TB) before discharge. Conclusions.-A
high proportion of patients with TB who failed outpatient therapy com
pleted treatment in a combined medical and psychosocial inpatient unit
. During the 5-year study period, involuntary admissions decreased and
most patients completed therapy as outpatients. In Massachusetts, thi
s program plays an important role in protecting public health and in p
roviding specialized medical management for patients to complete thera
py in a safe and supportive environment.