A HIGHLY STEREOCONTROLLED SYNTHETIC APPROACH TO 1,6-DIDEOXY-6,6-DIFLUOROAZASUGAR DERIVATIVES

Authors
KITAZUME T MURATA K OKABE A TAKAHASHI Y YAMAZAKI T
Citation
T. Kitazume et al., A HIGHLY STEREOCONTROLLED SYNTHETIC APPROACH TO 1,6-DIDEOXY-6,6-DIFLUOROAZASUGAR DERIVATIVES, Tetrahedron : asymmetry, 5(6), 1994, pp. 1029-1040
Citations number
30
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear","Chemistry Physical
Journal title
Tetrahedron : asymmetry → ACNP
ISSN journal
09574166
Volume
5
Issue
6
Year of publication
1994
Pages
1029 - 1040
Database
ISI
SICI code
0957-4166(1994)5:6<1029:AHSSAT>2.0.ZU;2-8
Abstract
The synthetic utility of (alpha R, 6R)- or (alpha R, hylbenzyl)-6-difl uoromethyl-5,6-dihydro-4-pyridone 2, which was produced from the react ion of 1-methoxy-3-[(trimethylsilyl)oxy]-1,3-butadiene and (alpha R)- or (alpha S)-N-(2,2-difluoroethylidene)methylbenzylamine 1, is describ ed. These materials are found to be potential intermediates for a high ly stereocontrolled synthesis of 1,6-dideoxy-6,6-difluoroazasugar anal ogues.