THE RESOLUTION OF TERTIARY ALPHA-ACETYLENE-ACETATE ESTERS BY THE LIPASE FROM CANDIDA-CYLINDRACEA

Authors
OHAGAN D ZAIDI NA
Citation
D. Ohagan et Na. Zaidi, THE RESOLUTION OF TERTIARY ALPHA-ACETYLENE-ACETATE ESTERS BY THE LIPASE FROM CANDIDA-CYLINDRACEA, Tetrahedron : asymmetry, 5(6), 1994, pp. 1111-1118
Citations number
19
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear","Chemistry Physical
Journal title
Tetrahedron : asymmetry → ACNP
ISSN journal
09574166
Volume
5
Issue
6
Year of publication
1994
Pages
1111 - 1118
Database
ISI
SICI code
0957-4166(1994)5:6<1111:TROTAE>2.0.ZU;2-F
Abstract
The resolution of tertiary alcohols using the Candida cylindracea lipa se is explored. In particular strategies are deployed to limit nonenzy matic hydrolysis of the tertiary acetate substrates in buffer, such th at a full range of the steric requirements and limitations for success ful resolutions can be explored.