A report of two cases of fluoroquinolones-associated Achilles tendon r
upture in two previously-healthy males is presented. Neither of them h
ad any other predisposing condition for this complication. Both were u
sed to strenous physical activity. No other cause could be found in re
lation to their traumatic experience. Emphasis is placed on the necess
ity of identifying this potential and probably unusual complication of
these widely-used antimicrobials.