STRUCTURAL STUDIES OF NEW MACROLIDE ANTIBIOTICS, SHURIMYCIN-A AND SHURIMYCIN-B

Authors
KUMAZAWA S ASAMI Y AWANE K OHTANI H FUKUCHI C MIKAWA T HAYASE T
Citation
S. Kumazawa et al., STRUCTURAL STUDIES OF NEW MACROLIDE ANTIBIOTICS, SHURIMYCIN-A AND SHURIMYCIN-B, Journal of antibiotics, 47(6), 1994, pp. 688-696
Citations number
20
Categorie Soggetti
Pharmacology & Pharmacy",Immunology
Journal title
Journal of antibiotics → ACNP
ISSN journal
00218820
Volume
47
Issue
6
Year of publication
1994
Pages
688 - 696
Database
ISI
SICI code
0021-8820(1994)47:6<688:SSONMA>2.0.ZU;2-N
Abstract
The structures of new antibiotics, shurimycins A and B produced by Str eptomyces hygroscopicus A1491, were elucidated from the physico-chemic al properties, 2D NMR techniques and chemical degradation experiments to be 36-membered macrolides related to azalomycins, scopafungin and g uanidylfungins. Shurimycins were active against fungi and Gram-positiv e bacteria.