BASE-LINE CORRELATES WITH QUALITY-OF-LIFE AMONG MEN AND WOMEN WITH MEDICATION-CONTROLLED HYPERTENSION - THE TRIAL OF NONPHARMACOLOGIC INTERVENTIONS IN THE ELDERLY (TONE)
Rt. Anderson et al., BASE-LINE CORRELATES WITH QUALITY-OF-LIFE AMONG MEN AND WOMEN WITH MEDICATION-CONTROLLED HYPERTENSION - THE TRIAL OF NONPHARMACOLOGIC INTERVENTIONS IN THE ELDERLY (TONE), Journal of the American Geriatrics Society, 45(9), 1997, pp. 1080-1085
OBJECTIVES: To examine Quality of Life (QOL) and its correlates among
older adults with medication-controlled hypertension. DESIGN: Baseline
data from the TONE clinical trial. MEASUREMENTS: Demographic variable
s (age, race, income), hypertension treatment (medication class, years
treated), health status (obesity, physical symptoms), and QOL status
(MOS-Short-Form 36, Jenkins Sleep Disturbance, and CES-D Depression).
PARTICIPANTS: A total of 975 men and women, aged 60 to 81 years and fr
ee of major diseases and disability, with a screening blood pressure (
BP) of less than or equal to 145/85 mm Hg, treated medically for hyper
tension with antihypertensive medication. RESULTS: On average, TONE pa
rticipants reported a QOL level on the SF-36 that was similar to or be
tter than that reported by older adults in the general population. How
ever, there was a strikingly high prevalence of physical complaints or
symptoms: 90.3% of men and 93.3% of women experienced one or more phy
sical symptoms or complaints, and nearly 50% reported that such sympto
ms had disrupted their daily functioning. Among variables considered,
only the physical symptoms index score,number of severe symptoms, and
obesity status were correlated consistently with QOL among TONE men an
d women. Lower QOL scores were associated with higher symptom scores a
nd with obesity. Neither medication class nor age were appreciably ass
ociated with QOL status. CONCLUSIONS: Physical symptoms, rather than m
edication class and age, were the strongest correlates of QOL in TONE.
This underscores the importance of identifying the etiology of sympto
ms as a means to improve the QOL of older hypertensive persons rather
than substituting medication. The association of poorer physical well-
being with obesity suggests that weight reduction to manage BP may als
o improve QOL for some individuals.