Y. Takesue et al., SURGICAL-TREATMENT FOR DUODENAL INVOLVEMENT IN CROHNS-DISEASE - REPORT OF A CASE, SURGERY TODAY-THE JAPANESE JOURNAL OF SURGERY, 27(9), 1997, pp. 858-862
A 29-year-old woman was hospitalized with a 1-month history of postpra
ndial epigastric pain, nausea, and vomiting, An upper gastrointestinal
tract X-ray series showed a marked narrowing of the pyloric region, A
histological examination of duodenal mucosal biopsy samples showed gr
anulomatous inflammation, and thus a diagnosis of intrinsic duodenal C
rohn's disease was made, A second upper gastrointestinal tract X-ray r
evealed a persistent gastric outlet obstruction, At laparotomy, the du
odenal wall was found to be thickened over a distance measuring 3.5 cm
in length from the pyloric ring, A longitudinal incision was made ol
er the entire length, up to 5.5 cm beyond the pyloric ring on either s
ide, while Finney-type anastomosis was also performed, A postoperative
upper gastrointestinal tract X-ray showed an improvement in the gastr
oduodenal passage. Enteral nutrition therapy was provided postoperativ
ely. Omeprazole was administered at a dose of 20 mg/day for 2 months.
The patient currently remains on maintenance therapy with famotidine a
t 20 mg/day and is clinically doing well.