REACTIONS OF TOXY-16-ALPHA,17-ALPHA-EPOXYPREGN-4-ENE-3,20-DIONE WITH NITROGEN-CONTAINING NUCLEOPHILIC AGENTS

Authors
PROTIVA J NGUYEN TTH URBAN J KLINOTOVA E
Citation
J. Protiva et al., REACTIONS OF TOXY-16-ALPHA,17-ALPHA-EPOXYPREGN-4-ENE-3,20-DIONE WITH NITROGEN-CONTAINING NUCLEOPHILIC AGENTS, Collection of Czechoslovak Chemical Communications, 62(7), 1997, pp. 1095-1104
Citations number
9
Categorie Soggetti
Chemistry
Journal title
Collection of Czechoslovak Chemical Communications → ACNP
ISSN journal
00100765
Volume
62
Issue
7
Year of publication
1997
Pages
1095 - 1104
Database
ISI
SICI code
0010-0765(1997)62:7<1095:ROTWN>2.0.ZU;2-#
Abstract
21-Acetoxy 16 alpha,17 alpha-epoxypregn-4-ene-3,20-dione (1) enters a reaction with acetonitrile catalyzed by perchloric acid, giving unusua l products with the furostane skeleton. In contrast to analogous react ions, the reaction with sodium azide results in the azido derivative p ossessing the non-rearranged ring D. The H-1 NMR, C-13 NMR, and mass s pectra are discussed.