Aa. Ernst et al., TOPICAL LIDOCAINE ADRENALINE TETRACAINE (LAT GEL) VERSUS INJECTABLE BUFFERED LIDOCAINE FOR LOCAL-ANESTHESIA IN LACERATION REPAIR, Western journal of medicine, 167(2), 1997, pp. 79-81
The objective of the study was to compare topical lidocaine adrenaline
tetracaine (LAT gel) with injectable buffered lidocaine with epinephr
ine regarding pain of application or injection and anesthesia effectiv
eness. The study was a randomized prospective comparison trial in an u
rban emergency department. Physicians and patients ranked the pain of
application, injection, and suturing according to a 10-cm visual analo
g scale. Sixty-six patients were entered, 33 in the LAT gel group and
33 in the injectable buffered lidocaine group. Injection was found to
be significantly more painful than application of gel (P < 0.001). For
anesthesia effectiveness, there was no difference according to patien
ts (P = 0.48) or physicians (P = 0.83) for topical vs injectable forms
. The number of sutures causing pain was not statistically different i
n the two groups (P = 0.28). In conclusion, LAT gel compared favorably
with injectable buffered lidocaine for local anesthesia effectiveness
and was significantly less painful to apply. It may be the preferred
local anesthetic for this reason.