CERVICAL-CANCER IN NEW-SOUTH-WALES WOMEN - 5-YEAR SURVIVAL, 1972 TO 1991

Citation
R. Taylor et al., CERVICAL-CANCER IN NEW-SOUTH-WALES WOMEN - 5-YEAR SURVIVAL, 1972 TO 1991, Australian and New Zealand journal of public health, 20(4), 1996, pp. 413-420
Citations number
33
Categorie Soggetti
Public, Environmental & Occupation Heath
ISSN journal
13260200
Volume
20
Issue
4
Year of publication
1996
Pages
413 - 420
Database
ISI
SICI code
1326-0200(1996)20:4<413:CINW-5>2.0.ZU;2-I
Abstract
We analysed five-year relative survival of 6992 cases of cervical canc er incident between 1972 and 1991 in New South Wales (NSW) women, usin g data from the population-based state Cancer Registry. Follow-up was to 1992. Survival was determined by record linkage to death certificat es. Relative survival was derived from absolute survival of cases with expected survival of age- and period-matched NSW women. Proportional hazard regression analysis was used for multivariate analysis. Relativ e survival at five years improved from 64 per cent in 1972-1976 to 72 per cent in 1987-1991, although the only significant increase occurred between 1972-1976 and 1977-1981 (64 to 70 per cent). Survival was bet ter for the age groups 0-39 years (RR 0.51) and 40-49 years (RR 0.63) and worse for the elderly (greater than or equal to 65 years) (RR 1.47 ) than for the referent group (50-64 years). Excess mortality was much less for those with localised disease (referent group), than for thos e with regional spread (RR 3.47) or metastatic cancer (RR 10.5) at dia gnosis. For the most recent period (1987-1991), relative five-year sur vival for localised disease was 82 per cent, for regional spread at di agnosis it was 49 per cent, and for metastatic cancer 21 per cent. Whe n adjusted for confounding, excess mortality was significantly higher for adenocarcinoma (RR 1.16) than for squamous cell carcinoma. Five-ye ar relative survival for cervical cancer in NSW women for the most rec ent period is similar to that in South Australia, and both compare fav ourably with international statistics. The lack of improvement of five -year survival for cervical cancer over 15 years since 1977-1981 reinf orces the importance of prevention through regular screening by cytolo gy.