THE STRUCTURE OF AN ACTIN-CROSS-LINKING DOMAIN FROM HUMAN FIMBRIN

Authors
GOLDSMITH SC POKALA M SHEN WY FEDOROV AA MATSUDAIRA P ALMO SC
Citation
Sc. Goldsmith et al., THE STRUCTURE OF AN ACTIN-CROSS-LINKING DOMAIN FROM HUMAN FIMBRIN, Nature structural biology, 4(9), 1997, pp. 708-712
Citations number
19
Categorie Soggetti
Biology,"Cell Biology
Journal title
Nature structural biology → ACNP
ISSN journal
10728368
Volume
4
Issue
9
Year of publication
1997
Pages
708 - 712
Database
ISI
SICI code
1072-8368(1997)4:9<708:TSOAAD>2.0.ZU;2-0
Abstract
The structure of the N-terminal actin binding domain of human fimbrin offers the first view of an F-actin crosslinking protein and is repres entative of the conserved actin binding domain found in the largest fa mily of crosslinking proteins. This domain is composed of two calponin homology domains and allows for the mapping of residues implicated in F-actin binding.