Ba. Franklin et al., CARDIOVASCULAR EVALUATION OF THE ATHLETE - ISSUES REGARDING PERFORMANCE, SCREENING AND SUDDEN CARDIAC DEATH, Sports medicine, 24(2), 1997, pp. 97-119
Recent studies have reported ECG anomalies and a high prevalence of ex
ercise related arrhythmias among well trained, apparently healthy endu
rance athletes with superior levels of cardiorespiratory fitness. The
occurrence of sudden and premature cardiac deaths in amateur and profe
ssional athletes, who appear to embody all of the virtues of health an
d fitness, has raised our consciousness regarding the underlying ather
osclerotic or nonatherosclerotic causes, and the need for, and extent
of, preparticipation screening in competitive athletes. It appears tha
t strenuous physical activity may trigger acute cardiovascular events
in some athletes. Coronary artery disease is the most frequent autopsy
finding in those over the age of 35 years who die suddenly. In contra
st, structural cardiovascular abnormalities, including hypertrophic ca
rdiomyopathy and malformations of the coronary arteries, are the major
cause of sudden death in younger athletes. This article reviews these
issues, with specific reference to the assessment of cardiorespirator
y fitness, legal and prohibited performance-altering medications, the
pathophysiological basis of exertion-related untoward events, the athl
ete at risk, limitations of conventional screening programmes and cont
emporary recommendations to identify latent cardiovascular disease in
athletic populations.