APPLICATION OF IMMUNOADSORPTION IN THE TH ERAPY OF GLOMERULONEPHRITIS

The therapy of glomerulonephritis is insufficient so far. An autoimmun e process with production of autoantibodies and formation of circulati ng immune complexes has been discussed in glomerulonephritis. The elim ination of pathogenetic relevant autoantibodies and Immune complexes c ould be important in these conditions. Immunoadsorption does selective ly remove immunoglobulins and is more effective than conventional plas ma exchange. Immunoadsorption can successfully be applied to patients suffering from rapidly progressive glomerulonephritis, focal and segme ntal glomerulosclerosis, lupus nephritis and Wegener's granulomatosis.