ELEVATED LEVELS OF CIRCULATING SOLUBLE ADHESION MOLECULES IN PERIPHERAL-BLOOD OF PATIENTS WITH UNSTABLE ANGINA

Authors
GHAISAS NK SHAHI CN FOLEY B GOGGINS M CREAN P KELLY A KELLEHER D WALSH M
Citation
Nk. Ghaisas et al., ELEVATED LEVELS OF CIRCULATING SOLUBLE ADHESION MOLECULES IN PERIPHERAL-BLOOD OF PATIENTS WITH UNSTABLE ANGINA, The American journal of cardiology, 80(5), 1997, pp. 617
Citations number
6
Categorie Soggetti
Cardiac & Cardiovascular System
Journal title
The American journal of cardiology → ACNP
ISSN journal
00029149
Volume
80
Issue
5
Year of publication
1997
Database
ISI
SICI code
0002-9149(1997)80:5<617:ELOCSA>2.0.ZU;2-8
Abstract
We have demonstrated increased levels of the circulating soluble adhes ion molecules (sCAMs), ICAM-1, VCAM-1, and E-selectin in patients with unstable angina compared with healthy controls. Our findings support the role of inflammation in clinically unstable coronary disease, and may indicate a potential role for measurement of peripheral sICAM leve ls as a marker for inflammatory activity in atherosclerotic plaque.