PARTIAL REVERSAL OF HEPARIN ANTICOAGULATION BY INTRAVENOUS PROTAMINE IN ABCIXIMAB-TREATED PATIENTS UNDERGOING PERCUTANEOUS INTERVENTION

Authors
KEREIAKES DJ BRODERICK TM WHANG DD ANDERSON L FYE D
Citation
Dj. Kereiakes et al., PARTIAL REVERSAL OF HEPARIN ANTICOAGULATION BY INTRAVENOUS PROTAMINE IN ABCIXIMAB-TREATED PATIENTS UNDERGOING PERCUTANEOUS INTERVENTION, The American journal of cardiology, 80(5), 1997, pp. 633
Citations number
5
Categorie Soggetti
Cardiac & Cardiovascular System
Journal title
The American journal of cardiology → ACNP
ISSN journal
00029149
Volume
80
Issue
5
Year of publication
1997
Database
ISI
SICI code
0002-9149(1997)80:5<633:PROHAB>2.0.ZU;2-E
Abstract
Serious hemorrhage and vascular complications after abciximab therapy are associated with elevated activated clotting time values. Our preli minary experience suggests that low-dose intravenous protamine adminis tration is both safe and effective in reducing elevated in-laboratory activated clotting time values and the potential for serious hemorrhag e in abciximab-treated patients.