K. Zafren et al., TREATMENT OF HIGH-ALTITUDE PULMONARY-EDEMA BY BED REST AND SUPPLEMENTAL OXYGEN, Wilderness & environmental medicine, 7(2), 1996, pp. 127-132
Study objectives: We evaluated the safety and efficacy of treating hig
h-altitude pulmonary edema (HAPE) by bed rest and supplemental oxygen
at moderate altitudes, We also characterized clinical parameters in HA
PE before and after treatment. Design: Case series. Setting: Two prima
ry care centers at about 9200 feet (2800 meters) above sea level, Type
of participants: All patients aged 16-69 years who had been diagnosed
with HAPE and were treated with bed rest and supplemental oxygen. Pat
ients were seen on a follow-up visit. Interventions: Selected patients
were treated with bed rest and supplemental oxygen rather than hospit
al admission or descent. Main outcome measure: Patients were considere
d improved on follow-up if room air arterial oxygen saturation was inc
reased by 10 percentage points or if their symptoms had improved. Resu
lts: Of 58 patients with confirmed HAPE, 25 (43%) were treated by bed
rest and supplemental oxygen and were seen on return visits to the cli
nic. All of the treated patients improved at the return visit. Systoli
c blood pressure, heart rate, respiratory rate, and temperature decrea
sed significantly between the first visit and the return visit. Oxygen
saturation improved between visits,Conclusion: Some patients with HAP
E at moderate altitudes where medical facilities are available can be
safely treated with bed rest and oxygen without descent.