PREGNANCY IN INFERTILE PCOD PATIENTS - COMPLICATIONS AND OUTCOME

OBJECTIVE: To evaluate the complications and outcome of pregnancy in w omen with polycystic ovary disease (PCOD). STUDY DESIGN: The course an d outcome of 47 singleton pregnancies in women with well-documented PC OD were compared with those in 100 healthy controls. RESULTS: Women wi th PCOD had a significantly higher body mass index as compared to the control group (P<.05); however, the proportion of lean versus obese su bjects in the two groups was similar. The incidence of an abnormal glu cose challenge test, gestational diabetes mellitus and pregnancy-induc ed hypertension was significantly increased in pregnant women with PCO D (P<.05). When lean PCOD subjects were compared with lean control sub jects, the difference in the incidence of the above complications was still significant (P<.05). The incidence of pregnancy complications wa s similar when obese PCOD subjects were compared with obese controls. CONCLUSION: Women with PCOD were at increased risk of gestational diab etes and pregnancy-induced hypertension, and this risk appeared to be independent of body mass index.