STERIC CONTROL OF OXIDATION SELECTIVITY IN MACROCYCLIC PHOSPHINE OXIDE-DITHIOETHERS

Authors
HOLMGREN SK SAVAGE PB DESPER JM SCHLADETZKY KD POWELL DR GELLMAN SH
Citation
Sk. Holmgren et al., STERIC CONTROL OF OXIDATION SELECTIVITY IN MACROCYCLIC PHOSPHINE OXIDE-DITHIOETHERS, Tetrahedron, 53(36), 1997, pp. 12249-12262
Citations number
25
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
53
Issue
36
Year of publication
1997
Pages
12249 - 12262
Database
ISI
SICI code
0040-4020(1997)53:36<12249:SCOOSI>2.0.ZU;2-X
Abstract
Macrocyclic phosphine oxide-disulfoxides 1a-e and 2a-e were synthesize d by oxidation of the corresponding dithioethers with m-CPBA. Four ste reoisomers are possible, but a single stereoisomer was isolated as the major product in each case. This paper describes the structural chara cterization of several trioxides as well as studies designed to determ ine the origin of oxidation selectivity. (C) 1997 Elsevier Science Ltd .