The brain may be affected by a variety of abnormalities in association
with human immunodeficiency virus (HIV) infection. Knowledge of their
existence and characteristic imaging features are important to radiol
ogists for detection, diagnosis, and initiation of an appropriate trea
tment. Although there is a considerable overlap in the imaging charact
eristics of different entities, some findings are found to be very sug
gestive of a particular disease. The CT and MR imaging techniques are
commonly used in the di agnosis of neurological disorders in acquired
immunodeficiency syndrome (AIDS) patients. to verify ;treatment respon
se and to guide brain biopsy. This re view attempts to describe CT and
MR features of infectious and malignant brain disorders in HIV-seropo
sitive patients.