Malignant gastrinoma is a nonbeta islet cell tumor which rarely dissem
inates to the bone. However, in the case reported herein, diffuse meta
static bone disease with symptomatic epidural spread developped. Somat
ostatin and 99mTc-HDP bone scans demonstrated hot spots in the same si
tes, establishing that the bone lesions contained somatostatin recepto
r. Irradiation was effective in relieving pain.