PRELIMINARY-RESULTS FROM CVD DIAMOND DETECTORS FOR BIOMOLECULAR IMAGING

Citation
Ar. Mahon et al., PRELIMINARY-RESULTS FROM CVD DIAMOND DETECTORS FOR BIOMOLECULAR IMAGING, Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment, 392(1-3), 1997, pp. 274-280
Citations number
15
Categorie Soggetti
Nuclear Sciences & Tecnology","Physics, Particles & Fields","Instument & Instrumentation",Spectroscopy
ISSN journal
01689002
Volume
392
Issue
1-3
Year of publication
1997
Pages
274 - 280
Database
ISI
SICI code
0168-9002(1997)392:1-3<274:PFCDDF>2.0.ZU;2-#
Abstract
An innovative biomolecular imaging system incorporating a Chemical Vap our Deposition diamond detector is in development. The synthetic diamo nd is used as a UV detector to image electrophoretically separated bio molecules. The microstrip diamond detectors have good quantum efficien cy, excellent UV response and low-leakage current. A deuterium lamp ha s been used with the detector to examine the UV properties of a ran of materials used in electrophoresis, Preliminary results are presented which include: UV sensitivity of the detector, diamond QE measurements and response time of the detector, Gel resolution and spatial resolut ion of the system are also presented, We discuss how the use of absorp tion-rather than emission-based detection combined with the UV propert ies of diamond may be used to decrease the amount of biological sample required and to reduce the electrophoretic imaging time significantly .