Ar. Mahon et al., PRELIMINARY-RESULTS FROM CVD DIAMOND DETECTORS FOR BIOMOLECULAR IMAGING, Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment, 392(1-3), 1997, pp. 274-280
An innovative biomolecular imaging system incorporating a Chemical Vap
our Deposition diamond detector is in development. The synthetic diamo
nd is used as a UV detector to image electrophoretically separated bio
molecules. The microstrip diamond detectors have good quantum efficien
cy, excellent UV response and low-leakage current. A deuterium lamp ha
s been used with the detector to examine the UV properties of a ran of
materials used in electrophoresis, Preliminary results are presented
which include: UV sensitivity of the detector, diamond QE measurements
and response time of the detector, Gel resolution and spatial resolut
ion of the system are also presented, We discuss how the use of absorp
tion-rather than emission-based detection combined with the UV propert
ies of diamond may be used to decrease the amount of biological sample
required and to reduce the electrophoretic imaging time significantly
.