CANCER INCIDENCE AMONG AN HIV-INFECTED COHORT

Authors
JOHNSON CC WILCOSKY T KVALE P ROSEN M STANSELL J REICHMAN L WALLACE J MARKOWITZ N THOMPSON JE HOPEWELL P HOPEWELL PC TURNER J OSMOND D MERRIFIELD C GLASSROTH J MOSSAR M HIRSCHTICK R ROSEN MJ MEISELMAN L MANGHISI KK SCHNEIDER RF REICHMAN LB MANGURA B BARNES S WALLACE JM RICHER B AU J COULSON A CLEMENTE V KVALE PA SARALOVATZ LD JOHNSON C HUITSING J KRYSTOFORSKI AM POOLE WK RAO AV CLAYTON K HANSEN N JORDAN M THOMPSON J MYERS D LAVANGE L KATZIN J FULKERSON W LOU Y KALICA R WITTES J FOLLMAN DA
Citation
Cc. Johnson et al., CANCER INCIDENCE AMONG AN HIV-INFECTED COHORT, American journal of epidemiology, 146(6), 1997, pp. 470-475
Citations number
28
Categorie Soggetti
Public, Environmental & Occupation Heath
Journal title
American journal of epidemiology → ACNP
ISSN journal
00029262
Volume
146
Issue
6
Year of publication
1997
Pages
470 - 475
Database
ISI
SICI code
0002-9262(1997)146:6<470:CIAAHC>2.0.ZU;2-5
Abstract
Malignancies, particularly Kaposi's sarcoma and non-Hodgkin's lymphoma (NHL), are associated with human immunodeficiency virus (HIV) infecti on, Cancer incidence among 1,073 asymptomatic HIV-infected individuals from the Pulmonary Complications of HIV infection Study cohort, perso ns from six states followed from 1988 to 1994, was examined, Total can cer incidence was 3.99/100 person-years; for Kaposi's sarcoma, inciden ce was 2.64 cases/100 person-years, and for NHL, it was 1.18 cases/100 person-years. Total cancer (n = 156 cases) was higher among nonblacks than among blacks (rate ratio = 2.8, 95% confidence interval 1.3-6.1) , with similar results far Kaposi's sarcoma and NHL. The rate of lung cancer (n = 5) among white, homosexual/bisexual males was 0.18 per 100 person-years, suggesting a high risk of lung cancer.