Ischemic colitis is caused by anoxia of the colonic and rectal wall du
e to defective regional blood supply. The pathology examination distin
guishes acute obstructive and non-obstructive gangrenous ischemic coli
tis from chronic segmentary stenosing ischemia on the basis of the gro
ss aspect and microscopic criteria and is necessary for differential d
iagnosis. Endoscopy, which is contraindicated in acute gangrenous isch
emic colitis, provides a biopsy. Acute transitory ischemia can be dist
inguished from chronic stenosing colitis.