S. Silvestri et S. Aronson, SEVERE HEAD-INJURY - PREHOSPITAL AND EMERGENCY DEPARTMENT MANAGEMENT, The Mount Sinai journal of medicine, 64(4-5), 1997, pp. 329-338
Head trauma causes approximately 75,000 deaths each year in the United
States. Both hypoxia and hypovolemia are individual predictors of poo
r outcome in the patient with severe head trauma. Management begins in
the field and is focused on ensuring oxygenation and maintaining a bl
ood pressure that supports cerebral perfusion. In the trauma center, i
ntracranial pressure monitoring may be helpful in guiding the manageme
nt of increased intracranial pressure. Mannitol, given in intermittent
bolus infusions, is the therapy of choice for increased intracranial
pressure. Hyperventilation has been shown to decrease cerebral perfusi
on and should be avoided; it is a temporizing procedure that is reserv
ed for those cases that demonstrate signs of increased intracranial pr
essure pending initiation of other therapies.