Congestive cardiomyopathy is a highly unusual complication of Wegener'
s granulomatosis, In this report, we describe a 37-year-old man with h
istologically proven Wegener's granulomatosis who had two episodes of
severe hypokinetic cardiomyopathy that responded well to cyclophospham
ide, The theory that cardiomyopathy might be related to cardiac involv
ement in Wegener's granulomatosis and the beneficial effect of cycloph
osphamide in this condition are discussed.