Fwg. Hill et al., LOCAL BACILLUS-CALMETTE-GUERIN THERAPY FOR BOVINE VULVAR PAPILLOMA AND CARCINOMA, Cancer immunology and immunotherapy, 39(1), 1994, pp. 49-52
Thirty cows from a pedigree Friesian dairy herd with bovine vulva papi
lloma and carcinoma were treated by intralesional injections of live b
acillus Calmette-Guerin (BCG). This treatment induced total regression
of all of six carcinomas. Whilst, after treatment, limited regression
was also observed in advanced papillomas, BCG has little or no effect
on the early stages of papillomas. This is the first study of BCG the
rapy in this type of cancer.