STUDY OF CORRELATIONS BETWEEN FINE-STRUCTURE OF BONDED LAYER AND AFFINITY PROPERTIES OF SILICAS WITH ATTACHED CYCLIC OLIGOPEPTIDES

Authors
MINGALYOV PG ORISHCHENKO NV FADEEV AY
Citation
Pg. Mingalyov et al., STUDY OF CORRELATIONS BETWEEN FINE-STRUCTURE OF BONDED LAYER AND AFFINITY PROPERTIES OF SILICAS WITH ATTACHED CYCLIC OLIGOPEPTIDES, Journal of chromatography, 777(2), 1997, pp. 249-259
Citations number
28
Categorie Soggetti
Chemistry Analytical","Biochemical Research Methods
Journal title
Journal of chromatography → ACNP
Volume
777
Issue
2
Year of publication
1997
Pages
249 - 259
Database
ISI
SICI code
Abstract
The cyclic oligopeptides bacitracin A and gramicidin S were immobilize d on epoxy-, tosyloxy- and halogenoalkyl-activated silicas. The sorben ts obtained were tested for affinity binding of proteinases. The effec ts of spacer length, ligand loading and the character of ligand attach ment (one-or poly-site) on the biospecific characteristics have been s tudied. (C) 1997 Elsevier Science B.V.